nitrous oxide and codeine the two maximize sedation. Keep away from or Use Alternate Drug. Limit use to people for whom alternate cure selections are inadequate
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benzhydrocodone/acetaminophen and codeine the two enhance sedation. Steer clear of or Use Alternate Drug. Restrict use to people for whom alternative treatment selections are insufficient
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Reserve concomitant prescribing of such medications in individuals for whom other cure selections are inadequate. Limit dosages and durations to the least needed. Watch closely more info for get more info signs of respiratory despair and sedation.
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celecoxib decreases effects of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Check. Prevents conversion of codeine to its Lively metabolite morphine.
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desipramine decreases results of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Helps prevent conversion of codeine to its Energetic metabolite morphine.
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clozapine decreases outcomes of codeine by impacting hepatic enzyme CYP2D6 metabolism. Use Caution/Keep an eye on. Prevents conversion of codeine check here to its Lively metabolite morphine.
Convey to your doctor If you're pregnant or Consider you may well be Expecting. Through pregnancy, this merchandise is not advisable. It might damage an unborn read more baby. Talk to your medical professional about the risks and benefits of this medication. See also Warning section.